| 2016 | 2015 | Institution | Country | Academic | Employer | Citations | H | Score |
| 1 | 1 | Harvard University | United States | 98.7 | 100.0 | 91.5 | 95.0 | 96.1 |
| 2 | 4 | University of Cambridge | United Kingdom | 93.8 | 95.6 | 95.3 | 92.0 | 93.9 |
| 3 | 3 | University of Oxford | United Kingdom | 93.4 | 98.7 | 95.3 | 91.0 | 93.8 |
| 4= | 12 | King's College London (KCL) | United Kingdom | 88.9 | 87.2 | 94.2 | 94.5 | 91.5 |
| 4= | 21 | Monash University | Australia | 100.0 | 73.7 | 88.2 | 88.2 | 91.5 |
| 6 | 8 | The University of Nottingham | United Kingdom | 93.8 | 65.9 | 99.1 | 89.9 | 91.4 |
| 7 | 6 | Karolinska Institute | Sweden | 84.3 | 88.4 | 95.7 | 96.0 | 90.5 |
| 8 | 5 | UCL (University College London) | United Kingdom | 88.6 | 84.7 | 91.5 | 94.0 | 90.3 |
| 9 | 16 | National University of Singapore (NUS) | Singapore | 88.0 | 74.5 | 98.1 | 91.5 | 90.1 |
| 10 | 15 | University of North Carolina, Chapel Hill | United States | 84.6 | 74.1 | 94.7 | 100.0 | 89.9 |
| 11 | 13 | Yale University | United States | 86.2 | 89.8 | 93.8 | 91.5 | 89.8 |
| 12 | 28 | Imperial College London | United Kingdom | 84.2 | 77.7 | 100.0 | 91.5 | 89.3 |
| 13 | 20 | University of California, San Diego (UCSD) | United States | 83.7 | 75.8 | 96.5 | 95.5 | 89.1 |
| 14 | 17= | The University of Manchester | United Kingdom | 89.2 | 70.7 | 95.2 | 89.9 | 89.0 |
| 15 | 2 | University of California, San Francisco (UCSF) | United States | 87.7 | 61.6 | 94.2 | 96.4 | 88.9 |
| 16 | 10 | The University of Tokyo | Japan | 89.7 | 88.3 | 88.4 | 82.8 | 87.5 |
| 17 | 14 | Johns Hopkins University | United States | 86.2 | 68.7 | 90.2 | 94.0 | 87.4 |
| 18 | 25= | Uppsala University | Sweden | 84.2 | 87.6 | 93.7 | 84.7 | 87.0 |
| 19 | 7 | University of Michigan | United States | 79.1 | 69.4 | 94.1 | 96.9 | 86.3 |
| 20 | 25= | ETH Zurich (Swiss Federal Institute of Technology) | Switzerland | 81.1 | 91.3 | 92.3 | 84.1 | 85.7 |
| 21= | 9 | Leiden University | Netherlands | 79.4 | 70.6 | 96.1 | 89.4 | 85.2 |
| 21= | 11 | Purdue University | United States | 77.4 | 68.5 | 96.9 | 92.5 | 85.2 |
| 21= | 17= | Seoul National University (SNU) | South Korea | 81.6 | 82.3 | 87.8 | 89.4 | 85.2 |
| 24 | 30 | University of Toronto | Canada | 75.9 | 89.3 | 88.6 | 94.0 | 84.9 |
| 25 | 24 | University of Copenhagen | Denmark | 75.8 | 70.0 | 93.3 | 95.0 | 84.4 |
| 26 | 33 | Ludwig-Maximilians-Universität München | Germany | 76.6 | 82.8 | 91.1 | 90.4 | 84.3 |
| 27 | 23 | Kyoto University | Japan | 81.8 | 81.8 | 87.9 | 85.3 | 84.2 |
| 28 | 39 | The University of Sydney | Australia | 79.8 | 74.6 | 89.7 | 88.8 | 84.0 |
| 29 | 38 | University of Washington | United States | 69.7 | 68.8 | 96.6 | 99.6 | 83.8 |
| 30 | 43= | Katholieke Universiteit Leuven | Belgium | 79.7 | 80.7 | 89.5 | 85.3 | 83.7 |
| 31 | 29 | University of British Columbia | Canada | 79.2 | 84.1 | 89.4 | 84.1 | 83.5 |
| 32 | 31 | University of Alberta | Canada | 74.5 | 80.9 | 91.5 | 90.4 | 83.4 |
| 33 | 27 | Duke University | United States | 71.0 | 80.1 | 92.9 | 91.0 | 82.4 |
| 34 | 43= | University of Geneva | Switzerland | 75.3 | 78.9 | 92.3 | 83.4 | 81.9 |
| 35= | 51-100 | Université de Montréal | Canada | 74.9 | 79.1 | 90.1 | 84.7 | 81.6 |
| 35= | 19 | University of Minnesota | United States | 73.2 | 65.5 | 91.4 | 91.5 | 81.6 |
| 37= | 51-100 | McGill University | Canada | 78.0 | 79.6 | 88.5 | 80.8 | 81.5 |
| 37= | 46= | The Chinese University of Hong Kong (CUHK) | Hong Kong | 72.7 | 82.0 | 92.7 | 84.1 | 81.5 |
| 39= | 51-100 | The University of Queensland (UQ) | Australia | 70.9 | 70.3 | 91.6 | 91.0 | 81.0 |
| 39= | 36= | University of Pennsylvania | United States | 67.1 | 88.4 | 90.9 | 90.4 | 81.0 |
| 41 | Utrecht University | Netherlands | 64.9 | 51.2 | 98.8 | 100.0 | 80.8 | |
| 42 | 22 | Peking University | China | 81.8 | 74.4 | 78.7 | 83.4 | 80.7 |
| 43 | 40= | University of Wisconsin-Madison | United States | 73.7 | 59.3 | 92.2 | 87.7 | 80.4 |
| 44 | 51-100 | Columbia University | United States | 70.8 | 85.2 | 91.0 | 82.8 | 80.3 |
| 45 | 34= | Freie Universität Berlin | Germany | 70.7 | 84.5 | 90.4 | 83.4 | 80.2 |
| 46= | 34= | University of Hong Kong (HKU) | Hong Kong | 79.5 | 69.9 | 87.2 | 78.0 | 80.1 |
| 46= | 32 | University of Southern California | United States | 72.8 | 70.6 | 93.4 | 82.2 | 80.1 |
| 48 | 51-100 | The University of Melbourne | Australia | 73.0 | 74.0 | 89.3 | 83.4 | 79.8 |
| 49 | 51-100 | University of Glasgow | United Kingdom | 77.0 | 48.7 | 94.5 | 80.1 | 79.3 |
| 50 | 40= | National Taiwan University (NTU) | Taiwan | 77.7 | 56.7 | 88.3 | 80.1 | 78.9 |